Myöhemmin borreliabakteerin DNA:ta löydettiin potilaalle ilmaantuneista lymfoomista. Potilas kuoli 9 v. myöhemmin.
Borrelial lymphocytoma-a historical case.
Sonck CE, Viljanen M, Hirsimaki P, Soderstrom KO, Ekfors TO.
APMIS. Oct; 106(10):947-52. 1998. PMID: 9833696
We here describe a patient with a tick bite in the areola mammae in 1953 followed by erythema migrans. Twenty years later, after another tick bite in the axillary skin, also followed by erythema migrans, a large lymphatic infiltrate developed in the mammary skin, when the margin of the erythema reached the areola. The infiltrate resolved within a year without any therapy.
Borrelial DNA was detected by polymerase chain reaction in the paraffin blocks of the lymphatic skin infiltrate. The patient died 9 years later of generalized lymphoma.